Protein Modification Reagents
Medchemexpress LLC Biotin-PEG2-C6-azide 50mg | 1011268-29-3 | 50 MG
Biotin-PEG2-C6-azide is a biotinylated PEG-based linker (CAS 1011268-29-3) containing an azide functional group used primarily in click chemistry and linker synthesis. It is supplied as a research reagent for conjugation, affinity capture, and PROTAC development.
- Contains a biotin tag for selective affinity capture of conjugates.
- Azide functional group enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- PEG2 spacer improves solubility and provides flexible linkage between groups.
- Appropriate for PROTAC linker synthesis, bioconjugation, and pull-down assays.
- Provided in small laboratory pack sizes suitable for research use.
Medchemexpress LLC OSu-PEG4-VC-PAB-MMAE | 1mg
OSu-PEG4-VC-PAB-MMAE involves in GDP-FAmP4MMAE (Monomethylauristatin E) synthesis which is for GDP label via site-specific conjugation[1]
Medchemexpress LLC Gly-gly-gly-PEG4-DBCO | 2353409-80-8 | 95.1% | 694.77 g/mol | C35H46N6O9 | 100 MG
Gly-gly-gly-PEG4-DBCO is a cleavable 4-unit polyethylene glycol (PEG4) linker bearing a DBCO (dibenzocyclooctyne) moiety for strain-promoted azide-alkyne cycloaddition. It is supplied as a dry powder intended for bioconjugation and antibody-drug conjugate (ADC) synthesis.
- Cleavable 4-unit PEG linker suitable for ADC synthesis.
- Contains a DBCO handle for copper-free click chemistry (SPAAC).
- High purity (95.1%) and molecular weight of 694.77 g/mol.
- Soluble in DMSO; ultrasonic assistance recommended for dissolution.
- Powder stable at -20°C; store solutions at -80°C for long-term stability.
Medchemexpress LLC Amino-PEG8-Boc | 756526-06-4 | 99.8% | 497.62 g/mol | C23H47NO10 | 100 MG
Amino-PEG8-Boc is a Boc-protected amino polyethylene glycol linker composed of eight ethylene glycol units. It is used as a cleavable spacer in antibody-drug conjugates (ADCs) and as a PEG-based linker in PROTAC synthesis, providing hydrophilicity and a reactive amine for further functionalization.
- Cleavable 8-unit PEG linker.
- Boc-protected amino terminus for selective deprotection and functionalization.
- Improves solubility and provides spacing between conjugated moieties.
- High purity (≈99.8%).
- Available in 100 mg packaging.
- Storage: pure form -20°C (long term) or 4°C (short term).
Medchemexpress LLC Tetrazine-PEG4-biotin | 99.3% | 660.78 | C30H44N8O7S | 5 MG
Tetrazine-PEG4-biotin is a cleavable 4-unit polyethylene glycol (PEG) linker that contains a tetrazine moiety and a biotin tag for bioorthogonal conjugation and affinity labeling in research applications. It undergoes rapid inverse electron demand Diels-Alder (iEDDA) reactions with trans-cyclooctene (TCO) partners and is supplied as a purple to purplish red solid intended for research use only.
- Cleavable 4-unit PEG linker suitable for antibody-drug conjugate synthesis.
- Facilitates rapid iEDDA click chemistry with TCO-containing molecules.
- Contains a biotin tag for affinity capture or detection.
- High purity reagent (99.3%) supplied as a purple to purplish red solid.
- Recommended storage at -20°C, protect from light; in solvent: -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC TCO-PEG3-Biotin | 99.9% | 570.74 g/mol | C27H46N4O7S | 10 MG
TCO-PEG3-Biotin is a cleavable three-unit PEG linker used for antibody-drug conjugate (ADC) synthesis and click-chemistry bioconjugation. It contains a trans-cyclooctene (TCO) moiety that reacts with tetrazine-functionalized partners via inverse electron-demand Diels-Alder (iEDDA) chemistry. This product is for research use only.
- Cleavable three-unit PEG linker suitable for ADC synthesis.
- Enables rapid iEDDA click chemistry with tetrazine-functionalized molecules.
- High purity: 99.9%.
- Molecular weight: 570.74 g/mol.
- Chemical formula: C27H46N4O7S.
- Appearance: white to off-white solid.
- Storage: powder at -20°C; in solvent store at -80°C up to 6 months or -20°C up to 1 month.
- Available quantity: 10 MG.
Medchemexpress LLC Mal-PEG4-bis-PEG4-propargyl | 1060.19 | C49H81N5O20 | 10 MG
Mal-PEG4-bis-PEG4-propargyl is a polyethylene glycol (PEG) based, cleavable linker designed for bioconjugation and antibody-drug conjugate (ADC) assembly. It features a thiol-reactive maleimide and an alkyne (propargyl) handle to enable both thiol conjugation and copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry, providing flexibility for payload attachment and linker assembly.
- Cleavable 8-unit PEG spacer for improved solubility and flexibility.
- Maleimide group for selective thiol conjugation to cysteine residues.
- Propargyl (alkyne) handle for CuAAC click chemistry.
- Suitable for synthesis of antibody-drug conjugates and other bioconjugates.
- Supplied as a 10 mg package for research-scale use.
Worthington Biochemical Corporation ELASTASE SUSPENSION 1GM
Two times crystallized. Supplied as an aqueous suspension. This preparation must be diluted to dissolve the enzyme. The diluted enzyme should be 0.22 micron filtered before use. Suitable for the isolation of Type II lung cells. 2594-83-7
